Senior Quality Control Analyst, CELLCore
Job Description Summary
STEMCELL’s Quality Control department has an opening for a Sr QC. Analyst, to join the CELLCore team. The Sr. QC Analyst will perform day to day operations related to cell bank manufacturing and quality control testing of master and working cell banks, perform subcloning and isotyping of hybridomas and other core cell bank facility activities. The role may also involve technology transfers, testing of finished products, in-process products and raw materials and performing experiments related to troubleshooting, stability testing and other product-related issues. This is a dynamic position that involves manufacturing, cell characterization and quality testing of cell banks used as in-process products and stem cell banks used in quality control final product testing. Our team looks for members who can collaborate effectively with other members of QC and other cross functional groups.
Duties and Responsibilities
Perform cell culture from thawing through cryopreservation and banking of hybridomas, CHO cells and other mammalian cell lines used for antibody and protein production
Perform subcloning of hybridomas by limiting dilution and evaluate supernatant antibody titre and specificity
Perform cell culture media adaptation techniques and characterization of cell lines
Perform specialized cell culture assays and techniques including monitoring cell proliferation, confluence, morphological assessment, cell health, cell identity/authentication and stability of cell lines
Maintain cultures of pluripotent stem cell maintenance and non-maintenance cell lines
Differentiate pluripotent stem cells into progenitor cells and other cell types of interest
Media and reagent preparation for conducting any assay as described. Preparation of cell banks to meet various project demands.
Perform a variety of cell based and analytical assays to evaluate in-process materials and products according to established Standard Operating Procedures (SOPs).
Development and improvement of QC testing procedures, writing or revising SOPs and working documents, reports or templates
Investigate and document out-of-specification results and non-conformances to support and maintain Quality Systems requirements
Complete batch records, analyze data and accurately complete QC testing reports using good documentation practices (GDP)
Complete SAP manufacturing operation duties for cell bank inventory and technology transfers
Apply a quality mindset and critical thinking skills to all aspects of work conducted
Communicate with supervisors and coworkers to promote a safe and cooperative working environment
BSc or MSc in Biology, Biochemistry or relevant area (emphasis on Cell Biology)
2+ years of industry experience in biotechnology or pharmaceutical industry or equivalent
Excellent laboratory skills including aseptic technique, cryopreservation and banking of cells and work experience in a cell culture environment, culturing varying 2D/3D cell lines
Knowledge of and follows good cell culture practice guidelines
Experience with live-cell imaging, cell subcloning , ELISA, antibody titre quantification and iso-typing is highly desirable
Previous experience in either a manufacturing setting or core facility is desirable
Ability to work with precision and accuracy
Excellent attention-to-detail and record-keeping skills
Excellent analytical, critical thinking & communication (oral & written) skills
Familiarity with ISO 13485 standards, Quality Systems and writing Standard Operating Procedures (SOPs)
Demonstrated ability to work cooperatively in a team setting
Proficiency with Microsoft Office Suite and Google Applications
STEMCELL Technologies Inc. is a privately-owned biotechnology company based in Vancouver that helps power leading-edge life science research around the world. Scientists performing stem cell, immunology, cancer, regenerative medicine and cellular therapy research are among those who rely on our cell culture media, cell separation products, instruments, ancillary reagents and contract assay services. We create novel, useful, standardized products of unfailing quality and deliver them to more than 70 countries via our many regional offices plus distribution centres in Vancouver, Seattle, Grenoble and Singapore. Driven by our love of science and our passion for quality, we see ourselves simply as “Scientists Helping Scientists” – standing by our customers to provide outstanding products, technical support and training. We have over 1000 science-oriented employees globally, including 250 PhDs/MScs, with most others holding a BSc or engineering degree. STEMCELL is proud to be the largest Biotechnology employer in Canada.
This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.
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Create an account by selecting the create account button. You will then be asked for your email and to create a password. Your Password must be eight characters long, contain at least one special character, one capital letter, and a number.Once you have created your password you will be asked to upload your resume. Uploading your resume will provide the ability to auto-populate your application with information from your resume. If you prefer to manually complete all of the fields in the application you can do this by clicking next. You can upload your cover letter as an attachment in the attachments screen. Thank you for your interest in STEMCELL!